Grid order, with Giancarlo

The 1998 Austrian Grand Prix was a Formula One motor race held at the A1-Ring on 26 July 1998. It was the tenth round of the 1998 FIA Formula One World Championship. A wet-dry qualifying session resulted in a mixed-up grid order, with Giancarlo Fisichella taking the first pole position of his career. The 71-lap race was won by Mika Häkkinen for McLaren, with teammate David Coulthard recovering to finish second, having been involved in two collisions during the race, and Michael Schumacher finishing third for Ferrari.

An exon junction complex (EJC) is a protein complex which forms on a pre-messenger RNA strand at the junction of two exons which have been joined together during RNA splicing. The EJC has major influences on translation, surveillance, localization of the spliced mRNA, and m⁶A methylation. It is first deposited onto mRNA during splicing and is then transported into the cytoplasm. There it plays a major role in post-transcriptional regulation of mRNA. It is believed that exon junction complexes provide a position-specific memory of the splicing event. The EJC consists of a stable heterotetramer core, which serves as a binding platform for other factors necessary for the mRNA pathway. The core of the EJC contains the protein eukaryotic initiation factor 4A-III bound to an adenosine triphosphate (ATP) analog, as well as the additional proteins Magoh and Y14. The binding of these proteins to nuclear speckled domains has been measured recently and it may be regulated by PI3K/AKT/mTOR signaling pathways. In order for the binding of the complex to the mRNA to occur, the eIF4AIII factor is inhibited, stopping the hydrolysis of ATP. This recognizes EJC as an ATP dependent complex. EJC also interacts with a large number of additional proteins; most notably SR proteins. These interactions are suggested to be important for mRNA compaction. The role of EJC in mRNA export is controversial.